Modafinil severe effects on the brain

Modafinil severe effects on the brainRecently, a research was conducted on the Modafinil medication. According to the research, Modafinil drug causes fewer side effects on the consumers and sometimes it induces dependency. But they have stated that this medicine causes lesser side effects compared to other cognitive enhancement medicines. They have tested 26 peoples and analyze the effect of the medicine on brain resting-state network activity and cognitive performances. Ms. Victoria, an expert physician and one of the members of the research team as she says,

“Only three-fourths of peoples is reacts to the medicine and rest of them are not react to the pill effects”.

Initially, Modafinil is prescribed only for the treatment of Attention Deficit Hyperactive Disorder and Narcolepsy. Later on, it is used to increase cognitive impairments in order to concentrate more on their activities. Nowadays this medicine become famous among the students and working professionals. But few of them are unaware of its severe effects on the brain. Here in this blog, you can able to know about the risk of brain issues from the usage of Modafinil drug.

Recent studies show the severe effect of “Smart Drug” Modafinil on the brain. Some students have taken the prescription medicines illegally in order to boost their energy, memory or attention levels. Recent animal studies show,

“Taking Modafinil medicine would lead to the long-term damage in the function of the brain”.

Researchers say,

“Modafinil medication that may enhance the performance of brain in the short period of time that seems to have lasting impacts on growing brains, making them less versatile for planning, multitasking and organizing”.


Dr. Wen-Jun Gao, a neuroscientist at Drexel University College of Medicine in Philadelphia said that human brains keep forming into a man’s 30s, especially the prefrontal cortex, a territory place where the decision-making and planning are involved [Source].

Taking too much of dosages of this medicine would increase the level of brain chemicals such as dopamine, norepinephrine, and serotonin. As a result of this, it could cause a severe impact on the drug user health. It was reported by the doctor Mr. Gao.


U.S Health department reports “Last Year 2017, nearly 5000 peoples were died due to the brain disorder”. They have analyzed that those peoples were used Modafinil frequently at higher doses. By that, they have suffered from severe side effects. Only a few peoples have undergone treatment yet they could also not alive even now. Doctors reported to their family members,

“The ingredients of Modafinil impacts the brain severely and lead them to suffer from brain disorder”.

One of the Narcolepsy patients states,

“Initially, Modafinil works effectively for me and I have taken this medicine periodically that assisted me to stay focused on my activities. Even I could not feel sleepy during my working hours without utilize of this medicine so I have decided to stop taking the medication. Within a few days, I have noticed some issues on my health. So I have consulted my physician as she said that I have been suffered from Neurodegenerative diseases. And my doctor says that this disorder would cause due to the effect of Modafinil on the brain”.

Usually, doctors prescribe a lower dosage of Modafinil for the treatment of narcolepsy and cognitive enhancement because that dose is sufficient to achieve the desired results. But few patients have misused the smart drug in an improper manner. Modafinil is a central nervous system stimulant yet the effectiveness of this medicine is quite high compared to other CNS stimulants on affecting the brain by increasing the level of brain chemicals in order to produce the calming effects. Dr.Richard says,

“ Modafinil is safe and effective when it is used properly according to the prescription label”.

Coming to the research studies, Modafinil drug helps to lift up the hypothalamic histamine levels in the brain. Histamine work as a modulator of different neurotransmitters that are linked to the brain. It plays a major role in increasing the capability of learning, promoting wakefulness, memory, eating, anxiety and locomotion. Some Modafinil dosages would enhance the level of histamine to a higher extent by that it enables the users to experience severe side effects.

This medicine might have the tendency to be modified the connectivity of brain and causes severe impacts on the brain chemicals. Even though this medicine is treated to the best one for cognitive enhancement, attaining more level of concentration, it holds the negative impacts. Users must know the features of this medicine prior to the utilize of it and even you can get the consultation from the doctor by that you might not experience any side effects. Still, researchers are finding out other effects of this medication.

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